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STEMCELL Technologies Inc easystep cd138 + magnetic nanoparticles
a Chemical structure of YL064. b U266 and MM1.S cells were treated with the indicated concentrations of YL064 for 24 h and apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, ## p < 0.01, compared with control annexin V+/PI+ cells. c U266 and MM1.S cells were untreated or treated with indicated concentrations of YL064 for 24 h. The indicated proteins were detected by western blot. d Primary <t>CD138</t> + MM cells were treated with YL064 (20 μM) for 24 h and CD138 + apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, # p < 0.05, ## p < 0.01, compared with control annexin V+/PI+ cells. e Primary PBMCs cells from healthy donors were treated with the indicated concentrations of YL064 (40 μM) for 24 h and cell viability was evaluated by Trypan blue exclusion assay
Easystep Cd138 + Magnetic Nanoparticles, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/easystep cd138 + magnetic nanoparticles/product/STEMCELL Technologies Inc
Average 90 stars, based on 1 article reviews
easystep cd138 + magnetic nanoparticles - by Bioz Stars, 2026-05
90/100 stars

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1) Product Images from "YL064 directly inhibits STAT3 activity to induce apoptosis of multiple myeloma cells"

Article Title: YL064 directly inhibits STAT3 activity to induce apoptosis of multiple myeloma cells

Journal: Cell Death Discovery

doi: 10.1038/s41420-018-0108-8

a Chemical structure of YL064. b U266 and MM1.S cells were treated with the indicated concentrations of YL064 for 24 h and apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, ## p < 0.01, compared with control annexin V+/PI+ cells. c U266 and MM1.S cells were untreated or treated with indicated concentrations of YL064 for 24 h. The indicated proteins were detected by western blot. d Primary CD138 + MM cells were treated with YL064 (20 μM) for 24 h and CD138 + apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, # p < 0.05, ## p < 0.01, compared with control annexin V+/PI+ cells. e Primary PBMCs cells from healthy donors were treated with the indicated concentrations of YL064 (40 μM) for 24 h and cell viability was evaluated by Trypan blue exclusion assay
Figure Legend Snippet: a Chemical structure of YL064. b U266 and MM1.S cells were treated with the indicated concentrations of YL064 for 24 h and apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, ## p < 0.01, compared with control annexin V+/PI+ cells. c U266 and MM1.S cells were untreated or treated with indicated concentrations of YL064 for 24 h. The indicated proteins were detected by western blot. d Primary CD138 + MM cells were treated with YL064 (20 μM) for 24 h and CD138 + apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, # p < 0.05, ## p < 0.01, compared with control annexin V+/PI+ cells. e Primary PBMCs cells from healthy donors were treated with the indicated concentrations of YL064 (40 μM) for 24 h and cell viability was evaluated by Trypan blue exclusion assay

Techniques Used: Double Staining, Control, Western Blot, Trypan Blue Exclusion Assay



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STEMCELL Technologies Inc easystep cd138 + magnetic nanoparticles
a Chemical structure of YL064. b U266 and MM1.S cells were treated with the indicated concentrations of YL064 for 24 h and apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, ## p < 0.01, compared with control annexin V+/PI+ cells. c U266 and MM1.S cells were untreated or treated with indicated concentrations of YL064 for 24 h. The indicated proteins were detected by western blot. d Primary <t>CD138</t> + MM cells were treated with YL064 (20 μM) for 24 h and CD138 + apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, # p < 0.05, ## p < 0.01, compared with control annexin V+/PI+ cells. e Primary PBMCs cells from healthy donors were treated with the indicated concentrations of YL064 (40 μM) for 24 h and cell viability was evaluated by Trypan blue exclusion assay
Easystep Cd138 + Magnetic Nanoparticles, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/easystep cd138 + magnetic nanoparticles/product/STEMCELL Technologies Inc
Average 90 stars, based on 1 article reviews
easystep cd138 + magnetic nanoparticles - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier

90
STEMCELL Technologies Inc easystep cd138+ magnetic nanoparticles
a Chemical structure of YL064. b U266 and MM1.S cells were treated with the indicated concentrations of YL064 for 24 h and apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, ## p < 0.01, compared with control annexin V+/PI+ cells. c U266 and MM1.S cells were untreated or treated with indicated concentrations of YL064 for 24 h. The indicated proteins were detected by western blot. d Primary <t>CD138</t> + MM cells were treated with YL064 (20 μM) for 24 h and CD138 + apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, # p < 0.05, ## p < 0.01, compared with control annexin V+/PI+ cells. e Primary PBMCs cells from healthy donors were treated with the indicated concentrations of YL064 (40 μM) for 24 h and cell viability was evaluated by Trypan blue exclusion assay
Easystep Cd138+ Magnetic Nanoparticles, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/easystep cd138+ magnetic nanoparticles/product/STEMCELL Technologies Inc
Average 90 stars, based on 1 article reviews
easystep cd138+ magnetic nanoparticles - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier

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a Chemical structure of YL064. b U266 and MM1.S cells were treated with the indicated concentrations of YL064 for 24 h and apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, ## p < 0.01, compared with control annexin V+/PI+ cells. c U266 and MM1.S cells were untreated or treated with indicated concentrations of YL064 for 24 h. The indicated proteins were detected by western blot. d Primary CD138 + MM cells were treated with YL064 (20 μM) for 24 h and CD138 + apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, # p < 0.05, ## p < 0.01, compared with control annexin V+/PI+ cells. e Primary PBMCs cells from healthy donors were treated with the indicated concentrations of YL064 (40 μM) for 24 h and cell viability was evaluated by Trypan blue exclusion assay

Journal: Cell Death Discovery

Article Title: YL064 directly inhibits STAT3 activity to induce apoptosis of multiple myeloma cells

doi: 10.1038/s41420-018-0108-8

Figure Lengend Snippet: a Chemical structure of YL064. b U266 and MM1.S cells were treated with the indicated concentrations of YL064 for 24 h and apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, ## p < 0.01, compared with control annexin V+/PI+ cells. c U266 and MM1.S cells were untreated or treated with indicated concentrations of YL064 for 24 h. The indicated proteins were detected by western blot. d Primary CD138 + MM cells were treated with YL064 (20 μM) for 24 h and CD138 + apoptotic cells were evaluated by Annexin V/PI double-staining assay. ** p < 0.01, compared with control annexin V+/PI– cells, # p < 0.05, ## p < 0.01, compared with control annexin V+/PI+ cells. e Primary PBMCs cells from healthy donors were treated with the indicated concentrations of YL064 (40 μM) for 24 h and cell viability was evaluated by Trypan blue exclusion assay

Article Snippet: The CD138-positive cells were selected using EasyStep CD138 + magnetic nanoparticles from MNCs (Stem Cell Technologies, Vancouver, BC, Canada) according to the manufacturer’s instructions.

Techniques: Double Staining, Control, Western Blot, Trypan Blue Exclusion Assay